Bleach 403 - Shadows Gone
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Credit and Thanks for summary: Bleach Wikipedia with modifications from me.
As a child, Shunsui Kyoraku often visited his older brother and his wife, the head of the Ise clan, a matriarchal family of priests cursed so that all male members die young.
The clan's sacred weapon, Shinken Hakkyoken, is passed down to female heirs and reflects the power of godlike beings back onto them.
After her husband's death, the Ise matriarch returns to her family with her unborn daughter Nanao, seeking to protect her from the blade's curse by secretly entrusting it to Shunsui. He conceals it inside his second Zanpakuto spirit, Okyo, created by Ohana, his first Zanpakuto spirit.
The Central 46 sentences Nanao's mother to death for losing the sacred treasure.
Nanao later enrolls in the Soul Reaper Academy, excelling at Kido and nearly joining the Kido Corps, but is instead assigned to Squad 8, where she unknowingly reunites with her uncle, Shunsui, who mentors her.
Back in the present day, Shunsui is critically wounded by Lille, who assumes a new angelic form in his Vollstandig and attacks with divine light. Nanao rejoins Shunsui, and using his Shikai, he hides them in Lille's shadow.
After revealing their shared history, Shunsui gives Nanao her inherited Zanpakuto. Despite being injured, Nanao uses Shinken Hakkyoken to sever Lille's arm. Uncle and Niece working together reflect Lille's ultimate blast, a massive trumpet-shaped energy bomb, back at him. It destroys most of Wahr Welt and severs Lille in half.
After the battle, Shunsui and Nanao collapse and begin to recover.